• our science our science Our Science
    • By Industry

      • Bioprocessing

        • Upstream

        • Downstream

        • Fill/Finish

        • Oligonucleotides

      • Cell and Gene Therapy

        • Upstream

        • Downstream

        • Fill/Finish

        • Oligonucleotides

      • Pharmaceutical

        • Oligonucleotides

        • Small Molecule

    • By Application

      • Buffer Prep

        • Chemical and Bioprocessing Containers

        • Filtration and Purification

      • Bulk Fill

      • Cell Growth

      • Cell Separation

        • Filtration and Purification

      • Facilities/Bulk Chemicals

        • Chemical and Bioprocessing Containers

      • Fill/Finish

      • Freezing

      • Media Prep

        • Filtration and Purification

      • Medical Devices

        • Dental

        • Eye Care

        • Implantable Devices

        • Medical Ultrasound

        • Wound Care

      • Quality Control

      • RNA and DNA Solutions

        • Oligonucleotides

      • Small Molecule

        • Liquid Filters

        • Catalysts

        • Ligands

        • Organophosphorus Compounds

        • Filtration and Purification

      • Storage

        • Chemical and Bioprocessing Containers

    • By Location

      • Hangzhou Facility

      • Life Sciences Technology Center

  • product catalog product catalog Product Catalog
    • Single-Use Assemblies

      • 2D and 3D Bags

      • Mixing Systems

      • Motion Bioreactor Bags

      • Microcarrier and Cell Separation Systems

      • Tube Sets and Manifolds

    • Filtration and Purification

      • Liquid Filters

      • Vent Gas Filters

    • Fluid Management

      • Tube Sets and Manifolds

      • Cynergy® Valves

      • Cynergy® Fittings

      • Custom Dip Tubes, Tanks, and Containers

      • Tubing and Pipe

    • Process Monitoring

      • Particle Characterization

    • Chemical Packaging

      • FluoroPure® HDPE Blowmolded Drums

        • FluoroPure® Trilayer HDPE Blowmolded Drums

        • FluoroPure® Advantage Trilayer HDPE Blowmolded Drums

      • NOWPak® Liner-Based Systems

      • FluoroPure® Composite Drums

      • FluoroPure® Intermediate Bulk Containers

      • Sentry® Quick Connect Systems

      • Rigid Bioprocessing Support Containers

    • Specialty Chemicals

      • Catalysts

      • Ligands

      • Organophosphorus Compounds

      • Siloxanes

      • Specialty Acrylates and Methacrylates

      • Specialty Additives

    • Premium Graphite

      • Life Sciences Graphite Grades

      • Premium Graphite Components

      • Graphite Processing Options

    • Liquid Filters

  • resources resources Resources
    • Industry Insights

      • Aramus™ Shaped 2D Single-Use Bags

      • Cell and Gene Therapy

      • Cold Chain Bioprocessing

      • Filter Bag Assembly

      • High-Density Cell Banking

      • Life Sciences Filtration

      • Low-Temperature Bioprocessing

      • Nanoparticles

      • Pandemic Response

      • Particle Characterization

      • Single-Use Solutions for Bioprocessing

      • USP Subvisible Particulate Testing

    • Reference Materials

    • Technical Information

      • Chemical Compatibility

      • Material Properties and Safety

      • Particle Characterization Applications

    • Entegris Blog

  • about us about us About Us
    • Corporate Overview

    • Corporate Social Responsibility

    • Careers

    • Events

    • Investor Relations

    • Legal/Trademark Notices

    • Locations

    • News Releases

    • Media Coverage

    • Entegris Blog

Bulk Fill


Products to fit your operation and protect end-stage bulk drug products while significantly reducing cost and risk.

The bulk filling stage of the downstream bioprocess involves significant resource investment in production, purification, and concentration. As a late-stage process, it can have a potential safety impact to the end user, who could be an already compromised patient. After a drug is bulk filled in a cleanroom, there are few safeguards to ensure its sterility. Partnering with us, we can make products to fit your operation and protect end-stage bulk drug products while significantly reducing cost and risk.  

We offer a variety of single-use products for the bulk fill process including bag assemblies, mixing systems, and custom tube sets and manifolds. We can configure them to fit your application requirements, providing closed system solutions for the last stages of your bioprocess. We partner with you in the design and configuration of bulk fill solutions and provide expertise to assure supply, quality, and timely delivery.

Featured Application Note

Large Volume Parenteral and Small Volume Parenteral Filtration

Featured Application Note

Large Volume Parenteral and Small Volume Parenteral Filtration

Featured Application Note

Large Volume Parenteral and Small Volume Parenteral Filtration