• our science our science Our Science

    • By Industry

      • Bioprocessing

        • Upstream

        • Downstream

        • Fill/Finish

        • Oligonucleotides

      • Cell and Gene Therapy

        • Upstream

        • Downstream

        • Fill/Finish

        • Oligonucleotides

      • Pharmaceutical

        • Oligonucleotides

        • Small Molecule

    • By Application

      • Buffer Prep

        • Chemical and Bioprocessing Containers

        • Filtration and Purification

      • Bulk Fill

      • Cell Growth

      • Cell Separation

        • Filtration and Purification

      • Facilities/Bulk Chemicals

        • Chemical and Bioprocessing Containers

      • Fill/Finish

      • Freezing

      • Media Prep

        • Filtration and Purification

      • Medical Devices

        • Dental

        • Eye Care

        • Implantable Devices

        • Medical Ultrasound

        • Wound Care

      • Quality Control

      • RNA and DNA Solutions

        • Oligonucleotides

      • Small Molecule

        • Liquid Filters

        • Catalysts

        • Ligands

        • Organophosphorus Compounds

        • Filtration and Purification

      • Storage

        • Chemical and Bioprocessing Containers

    • By Location

      • Hangzhou Facility

      • Life Sciences Technology Center

  • product catalog product catalog Product Catalog

    • Single-Use Assemblies

      • 2D and 3D Bags

      • Mixing Systems

      • Motion Bioreactor Bags

      • Microcarrier and Cell Separation Systems

      • Tube Sets and Manifolds

    • Filtration and Purification

      • Liquid Filters

      • Vent Gas Filters

    • Fluid Management

      • Tube Sets and Manifolds

      • Cynergy® Valves

      • Cynergy® Fittings

      • Custom Dip Tubes, Tanks, and Containers

      • Tubing and Pipe

    • Process Monitoring

      • Particle Characterization

    • Chemical Packaging

      • FluoroPure® HDPE Blowmolded Drums

        • FluoroPure® Trilayer HDPE Blowmolded Drums

        • FluoroPure® Advantage Trilayer HDPE Blowmolded Drums

      • NOWPak® Liner-Based Systems

      • FluoroPure® Composite Drums

      • FluoroPure® Intermediate Bulk Containers

      • Sentry® Quick Connect Systems

    • Specialty Chemicals

      • Catalysts

      • Ligands

      • Organophosphorus Compounds

      • Siloxanes

      • Specialty Acrylates and Methacrylates

      • Specialty Additives

    • Premium Graphite

      • Life Sciences Graphite Grades

      • Premium Graphite Components

      • Graphite Processing Options

    • Liquid Filters

  • resources resources Resources

    • Industry Insights

      • Aramus™ Shaped 2D Single-Use Bags

      • Cell and Gene Therapy

      • Cold Chain Bioprocessing

      • Filter Bag Assembly

      • High-Density Cell Banking

      • Life Sciences Filtration

      • Low-Temperature Bioprocessing

      • Nanoparticles

      • Pandemic Response

      • Particle Characterization

      • Single-Use Solutions for Bioprocessing

      • USP Subvisible Particulate Testing

    • Reference Materials

    • Technical Information

      • Chemical Compatibility

      • Material Properties and Safety

      • Particle Characterization Applications

    • Entegris Blog

  • about us about us About Us

    • Corporate Overview

    • Corporate Social Responsibility

    • Careers

    • Events

    • Investor Relations

    • Legal/Trademark Notices

    • Locations

    • News Releases

    • Media Coverage

    • Entegris Blog

Our Sites Our Sites Our Sites
more more More

Fill/Finish

Providing closed system solutions for the last stages of your bioprocess.

The sterile bulk fill operation for active pharmaceutical ingredient (API) and bulk drug substance (BDS) remains one of the most critical processes in biopharmaceutical manufacturing. This late-stage process has potential safety impacts to the end user. After a drug is bulk filled in a cleanroom, there are few safeguards to ensure its sterility. Partnering with us, we can make products to fit your operation and protect end-stage bulk drug products while significantly reducing cost and risk.

We offer a variety of single-use products and instruments used in the fill/finish process including our cold temperature compatible Aramus™ bag assemblies, mixing systems, custom tube sets and manifolds, as well as particle characterization and concentration instruments. We can configure them to fit your application requirements, providing closed system solutions for the last stages of your bioprocess. We partner with you in the design and configuration of bulk fill solutions and provide expertise to assure supply, quality, and timely delivery.

Featured Application Note

download-pdf
Overcoming Steam Challenges with Single-Use Assemblies
Download Now

Featured Application Note

download-pdf
Overcoming Steam Challenges with Single-Use Assemblies
Download Now

Featured Application Note

download-pdf
Overcoming Steam Challenges with Single-Use Assemblies
Download Now
Quality Control

We enable you to measure particles left over from filtration, in your single use bags, and most importantly in your parenteral drugs before injecting them into the patient.

2D and 3D Bags

We have quality single, double, and triple barrier containment systems to meet your safety, storage, and transportation needs of sterile liquids. We offer 2D barrier bag systems, 3D mulitlayer assembly bags, and Aramus™ assembly systems for cold temperature applications.
Tube Sets and Manifolds

With decades of experience, we can fabricate unique tube sets and manifolds to your exacting specifications. We have solutions for secure fluid transfer, aseptic filling, sterile processing or storage, bioreactor filtration and support, and so much more.