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Oligonucleotides

Our formulated drug compounds built with oligonucleotides can be used in therapeutics.

Our phosphitylating or phosphorylating compounds enable gene therapy manufacturers to engineer oligonucleotide sequences to match a complementary segment of DNA, for example to inhibit the expression of a gene. By blocking transcription, translation, or other gene expression and ultimately blocking protein synthesis, different pharmacological effects can be achieved, such as inhibiting a defective gene that could manifest and present as cancer. 

These formulated drug compounds built with oligonucleotides can be used in therapeutics where they are introduced into the body and can inhibit gene expression or provoke a biological response at the cellular level. 

Our oligonucleotide products can also be used in diagnostic applications such as genetic and forensic test kits. We proudly support these very high tech and fast-growing areas with our life sciences solutions.

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Quality Control

We enable you to measure particles left over from filtration, in your single use bags, and most importantly in your parenteral drugs before injecting them into the patient.

Tube Sets and Manifolds

With decades of experience, we can fabricate unique tube sets and manifolds to your exacting specifications. We have solutions for secure fluid transfer, aseptic filling, sterile processing or storage, bioreactor filtration and support, and so much more.
NOWPak® Liner-Based Systems

Rugged and efficient, Entegris NOWPak® liner based systems maintain chemical purity, maximize utilization and ensure safe transport, containment and dispense of valuable, ultraclean process fluids. A reliable, comprehensive portfolio of bottles, canisters, closures and accessories is available that enhance tool productivity, increase yields and reduce operating costs.
2D and 3D Bags

We have quality single, double, and triple barrier containment systems to meet your safety, storage, and transportation needs of sterile liquids. We offer 2D barrier bag systems, 3D mulitlayer assembly bags, and Aramus™ assembly systems for cold temperature applications.
Organophosphorus Compounds

We excel in the development and manufacturing of high-quality organophosphorus compounds for a wide range of applications from pharmaceuticals and industrial products to medical diagnostic reagents.