Bag Accessories
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Cassettes
We offer LN2 (liquid nitrogen) cassettes for use with Aramus™ single-use bag assemblies. At lower volumes, the Aramus single-use bag assemblies can be combined with LN2 cassettes to give them rigidity when handled and provide greater protection during freezing, storage, and thawing operations.
Freezing Shells
Made from high-quality stainless steel and heavy-duty plastic material, the freezing shells provide greater bulk drug substance (BDS) protection during handling, more consistent freezing/thawing, and reduced storage density.
Freezing Kits
Kits comprise a freezing shell and Cryo control unit (CCU) for that specific volume.
Cryo Control Unit Supports
CCU supports are available for use with the freezing shells. The CCU facilitates controlled freezing in standard static or blast freezers.
Casssettes
- Cell banking for bioreactor intensification
- Stem cell freezing and storage
- Cyrogenic storage of bulk drug or intermediates
- Cryogenic product shipment
- Process sampling and archiving
Freezing Shells
- Bulk drug storage and shipment
- Protection and storage of high value intermediates
- Bulk product fill
- Dry ice transport
Specifications
Dimensions
Cassettes |
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Part number | Width | Length | Height |
SU-FS-0.05-C2 | 16.0 cm (6.30") | 20.3 cm (7.98") | 2.0 cm (0.80") |
SU-FS-0.10-C2 | 16.1 cm (6.33") | 21.3 cm (8.40") | 2.0 cm (0.80") |
SU-FS-0.25-C2 | 15.7 cm (6.17") | 30.2 cm (11.90") | 2.2 cm (0.88") |
SU-FS-0.50-C2 | 19.1 cm (7.50") | 30.5 cm (12.00" | 2.3 cm (0.91") |
Freezing Shells |
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Part number | Width | Length | Height |
SU-FS-0001-01 | 208 mm (8.2") | 483 mm (13.7") | 37 mm (1.5") |
SU-FS-0002-01 | 288 mm (11.3") | 533 mm (21") | 37 mm (1.5") |
SU-FS-0005-01 | 358 mm (14.1") | 643 mm (25.3") | 52 mm (2.0") |
SU-FS-0010-01 | 408 mm (16.0") | 703 mm (27.7") | 70 mm (2.8") |
SU-FS-0020-01 | 503 mm (19.8") | 883 mm (34.8") | 70 mm (2.8") |
Performance Data
Cassettes
Average cooling rates, from 4°C to -40°C (39°F to -40°F), observed with Aramus bags stored in cassettes.
Data on rates shown in use with different freezers prior to storage in LN2 temperatures.
Standard lab freezer -80°C (-112°F) | Controlled plate freezer | |||
Bag size | At maximum fill | At minimum fill | At maximum fill | At minimum fill |
20 mL | -1.38°C (-2.49°F)/min | -1.28°C (-2.30°F)/min | -0.72°C (-1.30°F)/min | -0.66°C (-1.19°F)/min |
50 mL | -0.97°C (-1.74°F)/min | -1.30°C (-2.34°F)/min | -0.63°C (-1.13°F)/min | -0.77°C (-1.39°F)/min |
100 mL | -0.83°C (-1.50°F)/min | -1.31°C (-2.35°F)/min | -0.52°C (-0.94°F)/min | -0.80°C (-1.44°F)/min |
250 mL | -0.73°C (-1.31°F)/min | -1.30°C (-2.33°F)/min | -0.65°C (-1.16°F)/min | -0.84°C (-1.52°F)/min> |
500 mL | -0.53°C (-0.95°F)/min | -1.12°C (-2.02°F)/min | -0.64°C (-1.16°F)/min | -0.90°C (-1.61°F)/min |
Cassettes shown to increase robustness by maintaining bag integrity post-LN2 vapor phase storage.
Aramus bags in cassettes were frozen in LN2 vapor for 24 hours and then subjected to 12” drops three times:
Bag size | Fill volume | Drop test result |
20 mL | 20 mL | Pass (8/8) |
50 mL | 50 mL | Pass (8/8) |
100 mL | 100 mL | Pass (8/8) |
250 mL | 200 mL | Pass (8/8) |
500 mL | 350 mL | Pass (8/8) |
Cassettes |
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Aramus bag size* | 20 mL, 50 mL | 100 mL | 250 mL | 500 mL | |
Aramus fill volume (in cassette) | 10 – 20 mL, 35 – 50 mL | 50 – 100 mL | 70 – 200 mL | 100 – 350 mL | |
*Additional sizes are available upon request. | |||||
Freezing Shells |
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Aramus bag size | 1 L | 2 L | 5 L | 10 L | 20 L |
Maximum fill volume | 0.9 L | 1.7 L | 3.5 L | 6.5 L | 11.0 L |
Freezing shell part number | SU-FS-0001-01 | SU-FS-0002-01 | SU-FS-0005-01 | SU-FS-0010-01 | SU-FS-0020-01 |
Freezing shell weight | 1.96 kg (4.31 lbs) | 2.83 kg (6.23 lbs) | 4.45 kg (9.79 lbs) | 6.13 kg (13.49 lbs) | 8.73 kg (19.21 lbs) |
Maximum fill volumes are dependent on application, please contact Entegris to determine the optimal fill for your specific needs. Entegris also offers a range of cryo cassettes for volumes <1 L, see our cassettes datasheet for information. |
Successfully Opted for software Updates
Part Number | Compatible Aramus™ Bag Assembly | Product Type |
---|---|---|
SU-CC-0001-01 | 1 L | Cryo control unit (CCU) |
SU-CC-0002-01 | 2 L | Cryo control unit (CCU) |
SU-CC-0005-01 | 5 L | Cryo control unit (CCU) |
SU-CC-0010-01 | 10 L | Cryo control unit (CCU) |
SU-CC-0020-01 | 20 L | Cryo control unit (CCU) |
SU-FK-0001-01 | 1 L | Freezing kit |
SU-FK-0002-01 | 2 L | Freezing kit |
SU-FK-0005-01 | 5 L | Freezing kit |
SU-FK-0010-01 | 10 L | Freezing kit |
SU-FK-0020-01 | 20 L | Freezing kit |
SU-FS-0.05-C2 | 20 mL, 50 mL | Cassette |
SU-FS-0.10-C2 | 100 mL | Cassette |
SU-FS-0.25-C2 | 250 mL | Cassette |
SU-FS-0.50-C2 | 500 mL | Cassette |
SU-FS-0001-01 | 1 L | Freezing shell |
SU-FS-0002-01 | 2 L | Freezing shell |
SU-FS-0005-01 | 5 L | Freezing shell |
SU-FS-0010-01 | 10 L | Freezing shell |
SU-FS-0020-01 | 20 L | Freezing shell |
Cassettes
We offer LN2 (liquid nitrogen) cassettes for use with Aramus™ single-use bag assemblies. At lower volumes, the Aramus single-use bag assemblies can be combined with LN2 cassettes to give them rigidity when handled and provide greater protection during freezing, storage, and thawing operations.
Freezing Shells
Made from high-quality stainless steel and heavy-duty plastic material, the freezing shells provide greater bulk drug substance (BDS) protection during handling, more consistent freezing/thawing, and reduced storage density.
Freezing Kits
Kits comprise a freezing shell and Cryo control unit (CCU) for that specific volume.
Cryo Control Unit Supports
CCU supports are available for use with the freezing shells. The CCU facilitates controlled freezing in standard static or blast freezers.