Pharmsteri™ AHC PES Liquid Capsule and Cartridge Filter
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- Bioburden or sterile filtration for various process fluids
- Cell culture media and additives
- Process intermediates in mAb, vaccines, etc.
- Column or downstream unit protection
- High concentration buffers
- Bulk drug substances
- Protein solutions or formulations
- Other fouling or non-fouling fluids
Specifications
Capsules |
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| Size - Connections | Total Length - A | Body Diameter - B | Min Width - C | Max Width - D |
| 3-inch TC-TC | 154.5 mm (6.08”) | 96.0 mm (3.78”) | 107.0 mm (4.21”) | 153.0 mm (6.02”) |
| 3-inch TC-HB | 156.7 mm (6.17”) | 96.0 mm (3.78”) | 107.0 mm (4.21”) | 153.0 mm (6.02”) |
| 3-inch HB-HB | 159.7 mm (6.29”) | 96.0 mm (3.78”) | 107.0 mm (4.21”) | 153.0 mm (6.02”) |
| 5-inch TC-TC | 213.2 mm (8.39”) | 96.0 mm (3.78”) | 107.0 mm (4.21”) | 153.0 mm (6.02”) |
| 5-inch TC-HB | 216.5 mm (8.52”) | 96.0 mm (3.78”) | 107.0 mm (4.21”) | 153.0 mm (6.02”) |
| 5-inch HB-HB | 219.5 mm (8.96”) | 96.0 mm (3.78”) | 107.0 mm (4.21”) | 153.0 mm (6.02”) |
| 10-inch TC-TC | 335.5 mm (13.21”) | 96.0 mm (3.78”) | 107.0 mm (4.21”) | 153.0 mm (6.02”) |
| 10-inch TC-HB | 339.0 mm (13.35”) | 96.0 mm (3.78”) | 107.0 mm (4.21”) | 153.0 mm (6.02”) |
| 10-inch HB-HB | 342.0 mm (13.46”) | 96.0 mm (3.78”) | 107.0 mm (4.21”) | 153.0 mm (6.02”) |
Cartridges |
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| Size | Code 6 Dimension A | Code 7 Dimension A | ||
| 5" | 150.5 mm (5.9”) | 199.0 mm (7.8”) | ||
| 10" | 276.0 mm (10.9”) | 316.5 mm (12.5”) | ||
| 20" | 520.0 mm (20.5”) | 561.0 mm (22.1”) | ||
| 30" | 764.5 mm (30.1”) | 805.5 mm (31.7”) | ||
| 3”/5”/10” In-line Capsules | 5”/10”/20”/30” Cartridges | ||||
| Materials | Media | Polyethersulfone (PES) | Polyethersulfone (PES) | ||
| Support | Polypropylene | Polypropylene | |||
| Core, cage, end caps | Polypropylene | Polypropylene | |||
| O-ring | Silicone | Silicone | |||
| Sealing technology | Thermal bonding without adhesives | Thermal bonding without adhesives | |||
| Pore size | 0.45+0.22 μm | 0.45+0.22 μm | |||
| 0.65+0.22 μm | 0.65+0.22 μm | ||||
| Filtration area | 3" | 0.15 m2 | 5" | 0.28 m2 | |
| 5" | 0.28 m2 | Per 10" | 0.55 m2 | ||
| 10" | 0.55 m2 | ||||
| Integrity | Bubble point | ≥3.65 bar (53 psi) air with water | ≥3.65 bar (53 psi) air with water | ||
| Water Diffusion | 3" | ≤ 6.8 mL/min @ 40 psi at 25°C | 5" | ≤ 11 mL/min @ 40 psi at 25°C | |
| 5" | ≤ 10.5 mL/min @ 40 psi at 25°C | Per 10" | ≤ 21 mL/min @ 40 psi at 25°C | ||
| 10" | ≤ 21 mL/min @ 40 psi at 25°C | ||||
| Maximum operating conditions | Maximum operating pressure | 80 psi (5.5 bar) @ 25°C (77°F) | 80 psi (5.5 bar) @ 25°C (77°F) | ||
| 40 psi (2.8 bar) @ 60°C (140°F) | 29 psi (2.0 bar) @ 80°C (176°F) | ||||
| Maximum differential pressure | Forward 60 psi (4.1 bar) @ 25°C (77°F) | Forward 60 psi (4.2 bar) @ 25°C (77°F) | |||
| Forward 30 psi (2.1 bar) @ 60°C (140°F) | Forward 29 psi (2.0 bar) @ 80°C | ||||
| Reverse 10 psi (0.7 bar) @25°C (77°F) | Reverse 10 psi (0.7 bar) @ 25°C (77°F) | ||||
| Bacteria Retention | >107 CFU/cm2 B. diminuta per the ASTM F838 | >107 CFU/cm2 B. diminuta per the ASTM F838 | |||
| Multiple sterilization cycles | 25 cycles of autoclave, 30 min at 127°C (260.6°F) | 25 cycles of autoclave, 30 min at 127°C (260.6°F), or 25 cycles of 30 min steam in place (SIP) at 131°C with differential pressure under 300 mbar | |||
| Endotoxin releasing | <0.25 EU/mL as determined by the LAL test, meeting the requirements of USP <85> | ||||
| Particulates | Particulate matter release meets the requirement of USP <788> | ||||
| Non-fiber releasing | Manufactured with non-fiber release materials and tested according to 21 CFR 210.3 (b) (6) | ||||
| TOC | <0.5 mg/L post autoclave and after a water flush, meeting the requirements of USP <643> | ||||
| Conductivity | ≤1.3 µS/cm post autoclave and after water flush, meeting the requirements of USP <645> | ||||
| Material toxicity | All components meet the requirements of the USP <87>, Biological Reactivity Test and the USP <88> Reactivity Test for Class VI Plastics | ||||
| Animal Free | Raw materials used to manufacture this product are not animal derived, meeting the EU directive for animal free CPMP EMA/410/01 and 21 CFR parts 189.5 | ||||
| Extractables | Tested according to BioPhorum Operations Group (BPOG) guideline. Report is available upon request. | ||||
| Quality | 100% integrity tested, manufactured in accordance with ISO 9001 and ISO 13485 certified quality management system | ||||
Successfully Opted for software Updates
| Part Number | Form Factor | Size | Length | Retention Rating | Connection | Inlet and Outlet Connection | Packaging Configuration |
|---|---|---|---|---|---|---|---|
| PSTACSD042HS03-2 | Capsule | 3" capsule | N/A | 0.45 + 0.22 µm | N/A | 1/2" hose barb | 2 ea/box |
| PSTACSD042HS05-1 | Capsule | 5" capsule | N/A | 0.45 + 0.22 µm | N/A | 1/2" hose barb | 1 ea/box |
| PSTACSD042HS10-1 | Capsule | 10" capsule | N/A | 0.45 + 0.22 µm | N/A | 1/2" hose barb | 1 ea/box |
| PSTACSD042TH03-2 | Capsule | 3" capsule | N/A | 0.45 + 0.22 µm | N/A | 1.5" sanitary TC inlet and 1/2" hose barb outlet | 2 ea/box |
| PSTACSD042TH05-1 | Capsule | 5" capsule | N/A | 0.45 + 0.22 µm | N/A | 1.5" sanitary TC inlet and 1/2" hose barb outlet | 1 ea/box |
| PSTACSD042TH10-1 | Capsule | 10" capsule | N/A | 0.45 + 0.22 µm | N/A | 1.5" sanitary TC inlet and 1/2" hose barb outlet | 1 ea/box |
| PSTACSD042TS03-2 | Capsule | 3" capsule | N/A | 0.45 + 0.22 µm | N/A | 1.5" sanitary TC | 2 ea/box |
| PSTACSD042TS05-1 | Capsule | 5" capsule | N/A | 0.45 + 0.22 µm | N/A | 1.5" sanitary TC | 1 ea/box |
| PSTACSD042TS10-1 | Capsule | 10" capsule | N/A | 0.45 + 0.22 µm | N/A | 1.5" sanitary TC | 1 ea/box |
| PSTACSD062HS03-2 | Capsule | 3" capsule | N/A | 0.65 + 0.22 µm | N/A | 1/2" hose barb | 2 ea/box |
| PSTACSD062HS05-1 | Capsule | 5" capsule | N/A | 0.65 + 0.22 µm | N/A | 1/2" hose barb | 1 ea/box |
| PSTACSD062HS10-1 | Capsule | 10" capsule | N/A | 0.65 + 0.22 µm | N/A | 1/2" hose barb | 1 ea/box |
| PSTACSD062TH03-2 | Capsule | 3" capsule | N/A | 0.65 + 0.22 µm | N/A | 1.5" sanitary TC inlet and 1/2" hose barb outlet | 2 ea/box |
| PSTACSD062TH05-1 | Capsule | 5" capsule | N/A | 0.65 + 0.22 µm | N/A | 1.5" sanitary TC inlet and 1/2" hose barb outlet | 1 ea/box |
| PSTACSD062TH10-1 | Capsule | 10" capsule | N/A | 0.65 + 0.22 µm | N/A | 1.5" sanitary TC inlet and 1/2" hose barb outlet | 1 ea/box |
| PSTACSD062TS03-2 | Capsule | 3" capsule | N/A | 0.65 + 0.22 µm | N/A | 1.5" sanitary TC | 2 ea/box |
| PSTACSD062TS05-1 | Capsule | 5" capsule | N/A | 0.65 + 0.22 µm | N/A | 1.5" sanitary TC | 1 ea/box |
| PSTACSD062TS10-1 | Capsule | 10" capsule | N/A | 0.65 + 0.22 µm | N/A | 1.5" sanitary TC | 1 ea/box |
| PSTSAD42605S1 | Cartridge | 5" capsule | 5" | 0.45 + 0.22 µm | Code 6 | N/A | N/A |
| PSTSAD42610S1 | Cartridge | 5" capsule | 10" | 0.45 + 0.22 µm | Code 6 | N/A | N/A |
| PSTSAD42620S1 | Cartridge | 5" capsule | 20" | 0.45 + 0.22 µm | Code 6 | N/A | N/A |
| PSTSAD42630S1 | Cartridge | 10" capsule | 30" | 0.45 + 0.22 µm | Code 6 | N/A | N/A |
| PSTSAD42705S1 | Cartridge | 5" capsule | 5" | 0.45 + 0.22 µm | Code 7 | N/A | N/A |
| PSTSAD42710S1 | Cartridge | 5" capsule | 10" | 0.45 + 0.22 µm | Code 7 | N/A | N/A |
| PSTSAD42720S1 | Cartridge | 5" capsule | 20" | 0.45 + 0.22 µm | Code 7 | N/A | N/A |
| PSTSAD42730S1 | Cartridge | 10" capsule | 30" | 0.45 + 0.22 µm | Code 7 | N/A | N/A |
| PSTSAD62605S1 | Cartridge | 5" capsule | 5" | 0.65 + 0.22 µm | Code 6 | N/A | N/A |
| PSTSAD62610S1 | Cartridge | 5" capsule | 10" | 0.65 + 0.22 µm | Code 6 | N/A | N/A |
| PSTSAD62620S1 | Cartridge | 5" capsule | 20" | 0.65 + 0.22 µm | Code 6 | N/A | N/A |
| PSTSAD62630S1 | Cartridge | 10" capsule | 30" | 0.65 + 0.22 µm | Code 6 | N/A | N/A |
| PSTSAD62705S1 | Cartridge | 5" capsule | 5" | 0.65 + 0.22 µm | Code 7 | N/A | N/A |
| PSTSAD62710S1 | Cartridge | 5" capsule | 10" | 0.65 + 0.22 µm | Code 7 | N/A | N/A |
| PSTSAD62720S1 | Cartridge | 5" capsule | 20" | 0.65 + 0.22 µm | Code 7 | N/A | N/A |
| PSTSAD62730S1 | Cartridge | 10" capsule | 30" | 0.65 + 0.22 µm | Code 7 | N/A | N/A |