Pharmsteri APFS PES Liquid Cartridge Filter

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Allows end users to perform lab scale scalability study and easily scale up to pilot and commercial manufacturing.

Highly asymmetric membrane minimize pressure build-up while processing large volume challenging fluids
Broad chemical compatibility pH 1~14, allows use in a range of chemicals including acids and bases
Product has been rigorously validated to product specification and industry standards with comprehensive documentation to support compliance

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Applications Pharmsteri APFS PES Liquid Cartridge Filter Applications

Process intermediates in mAb, vaccines, etc.
Bulk drug substances
Protein solutions or formulations
Other fouling fluids

Specifications

Drawings

Size	Code 6 Dimension A	Code 7 Dimension A
5"	150.5 mm (5.9”)	199.0 mm (7.8”)
10"	276.0 mm (10.9”)	316.5 mm (12.5”)
20"	520.0 mm (20.5”)	561.0 mm (22.1”)
30"	764.5 mm (30.1”)	805.5 mm (31.7”)

Performance Data

Product Specifications

Materials	Media	Asymmetric Polyethersulfone
	Support	Polypropylene
	Core, cage, end caps	Polypropylene
	O-ring	Silicone
Sealing technology		Thermal bonding without adhesives
Retention rating		0.45 μm, 0.65 μm
Filtration area		5"	0.3 m²
		Per 10"	0.6 m²
Integrity	Minimum bubble point@ 25°C (77°F)	0.45 μm	≥2.3 bar (33.3 psi) air with water
		0.65 μm	≥1.3 bar (18.8psi) air with water
	Maximum water diffusion flow @ 25°C (77°F)	0.45 μm, 5"	≤ 11 mL/min @ 1500 mbar (21.7 psi)
		0.45 μm, Per 10"	≤ 20 mL/min @ 1500 mbar (21.7 psi)
		0.65 μm, 5"	≤ 8 mL/min @ 600 mbar (8.7 psi)
		0.65 μm, Per 10"	≤ 15 mL/min @ 600 mbar (8.7 psi)
Maximum operating conditions	Maximum forward differential pressure	61 psi (4.2 bar) @ 25°C (77°F)
		29 psi (2.0 bar) @ 80°C
	Maximum operating temperature	80°C (176°F)
Multiple sterilization cycles		25 cycles of autoclave, 30 min at 127°C (260.6°F), or 25 cycles of 30 min steam in place (SIP) at 131°C with differential pressure under 300 mbar
Endotoxin releasing	<0.25 EU/mL as determined by the LAL test, meeting the requirements of USP <85>
Particulates	Particulate matter release meets the requirement of USP <788>
Non-fiber releasing	Manufactured with non-fiber release materials and tested according to 21 CFR 210.3 (b) (6)
TOC	<0.5 mg/L post gamma and after a water flush, meeting the requirements of USP <643>
Conductivity	≤1.3 µS/cm post gamma and after water flush, meeting the requirements of USP <645>
Material toxicity	All components meet the requirements of the USP <87>, Biological Reactivity Test and the USP <88> Reactivity Test for Class VI Plastics
Animal Free	Raw materials used to manufacture this product are not animal derived, meeting the EU directive for animal free CPMP EMA/410/01 and 21 CFR parts 189.5
Extractables	Tested according to BioPhorum Operations Group (BPOG) guideline. Report is available upon request.
Quality	100% integrity tested, manufactured in accordance with ISO 9001 and ISO 13485 certified quality management system

Successfully Opted for software Updates

Reference Materials Product Documentation

Published Jun 20, 2025 Data Sheet Pharmsteri APFS PES Liquid Cartridge Filter

242.3 kB

Published Jun 20, 2025 Data Sheet Pharmsteri APFS PES Liquid Cartridge Filter - A4

242.4 kB

Part Numbers

Pharmsteri APFS PES Liquid Cartridge Filter Part Numbers

Part Number	Retention Rating	Connection	Length	O-ring	Packaging Configuration
PSTSA045605S1	0.45 µm	Code 6	5"	Silicone	1 ea/box
PSTSA045610S1	0.45 µm	Code 6	10"	Silicone	1 ea/box
PSTSA045620S1	0.45 µm	Code 6	20"	Silicone	1 ea/box
PSTSA045630S1	0.45 µm	Code 6	30"	Silicone	1 ea/box
PSTSA045705S1	0.45 µm	Code 7	5"	Silicone	1 ea/box
PSTSA045710S1	0.45 µm	Code 7	10"	Silicone	1 ea/box
PSTSA045720S1	0.45 µm	Code 7	20"	Silicone	1 ea/box
PSTSA045730S1	0.45 µm	Code 7	30"	Silicone	1 ea/box
PSTSA065605S1	0.65 µm	Code 6	5"	Silicone	1 ea/box
PSTSA065610S1	0.65 µm	Code 6	10"	Silicone	1 ea/box
PSTSA065620S1	0.65 µm	Code 6	20"	Silicone	1 ea/box
PSTSA065630S1	0.65 µm	Code 6	30"	Silicone	1 ea/box
PSTSA065705S1	0.65 µm	Code 7	5"	Silicone	1 ea/box
PSTSA065710S1	0.65 µm	Code 7	10"	Silicone	1 ea/box
PSTSA065720S1	0.65 µm	Code 7	20"	Silicone	1 ea/box
PSTSA065730S1	0.65 µm	Code 7	30"	Silicone	1 ea/box