Join Us | BOOTH 612
Entegris offerings include 2D and 3D bag assemblies, sterile filtration, and a U.S.-based Life Sciences Technology Center specializing in freeze/thaw. With a global footprint and local representation, we can guarantee a reliable and responsive supply chain that incorporates the latest research and best practices. We also provide more than just a large catalog. Talk to our experts and learn how we offer custom products and support backed by decades of experience, then discover how you can easily adapt Entegris’ life sciences solutions into your unique workflows.
FEATURED PRESENTATION
November 13, 2:30 – 2:50 p.m.
Particles: Single-Use Material Risk Mitigation in Bioprocess Operations
Particle contamination in parenteral drugs poses significant risks to patient safety and therapeutic efficacy. Contaminants, including fibers, plastic fines, glass, rubber, and metal, can originate from various sources during manufacturing, packaging, and handling processes. However, a unique challenge arises when the drug itself consists of particles, such as in nanoparticle-based formulations or cell therapies.
To mitigate these dangers, a comprehensive approach involving collaboration between N-1 and N-2 supply chain partners can significantly reduce particle contamination risk. By aligning quality standards, sharing data, and fostering open communication, N-1 and N-2 suppliers can establish a more resilient supply chain. This improves yield and ensures that particle contamination is effectively minimized while maintaining the integrity of particle-based drugs. This collaborative framework not only strengthens the overall quality assurance program but also supports the development of safer and more effective parenteral therapies.
ABOUT THE ENTEGRIS PRESENTER
Donnie Beers, Life Sciences Applications Leader, Cell and Gene Therapy, Entegris
Donnie has nearly 15 years’ experience working in single-use and automation technology in biopharma. Donnie joined Entegris in 2019 as Senior Product Manager for single-use products and has since taken a lead role in helping customers overcome unique challenges in cell and gene therapies. He has previously held roles in engineering management, project management, and manufacturing within a cGMP environment. Donnie earned his Bachelor of Science in biochemistry from the University of Wisconsin – Madison.
Event Related Content
Our Life Sciences Technology Center is your gateway to cutting-edge freeze/thaw technology and support. We provide everything needed to make educated decisions about which freezing processes and products best fit your needs.
Entegris, a world-class supplier of advanced materials and process solutions for the semiconductor industry, brings over 50 years of contamination control expertise and supply chain strength to life sciences customers around the world. Our technologies help improve purity and yield in a wide range of pharmaceutical applications, including COVID-19 vaccine manufacturing.
Aramus 2D single-use bags provide high purity, exceptional compatibility, and increased safety for critical process fluids and final products. These robust solutions are now available in custom shapes, sizes, and assembly configurations to optimize your processes.
Many cell and gene therapies such as CAR-T and mRNA vaccines require repeated freezing and thawing during production, storage, and delivery. Aramus single-use assemblies are ideal for protecting and optimizing the cold-chain freeze/thaw processes for these precious treatments. Our 2D bag material selection, designs, and secondary protective shells, along with our Aramus assemblies, can substantially reduce the risks associated with cell and gene therapy storage and transport.