Single-Use Solutions for Bioprocessing
Our single-use solutions are customizable to fit into any bioprocess including cell growth, separation, mixing, and storage. We combine product innovation and quick-turn response to deliver critical solutions for your upstream and downstream operations. Our comprehensive set of bag solutions, bioreactors, mixing systems, and microcarrier separation systems meet the emerging requirements of fast-growing, single-use bioprocessing applications. At the onset of the pandemic, we committed to being a strong partner; we significantly increased our capacity and have maintained critical operations by relying on our business continuity plans and leveraging trusted supply partnerships.
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A Trusted Partner
Supported by proven expertise and strong manufacturing and supply chain managment to ensure your process integrity.
Design Expertise
Quick-Turn
Configuration and CustomizationSecure Supply
Enable Your Process
Culture Cells
Separate and Wash
Microcarrier Separation Systems
Microcarrier bead and cell separation
0.5 L to 50 L
Mesh sizes X-Y µm
Mix
Recirculating Mixer
Pump driven
Low wear
Compatible with existing or Entegris supplied hardware
50 L to 500 L
Multilayer PE Film
Store and Process
Storage Bags
500 mL to 1,000 L
Tube Sets Including Filters
Wide array of tubing material and connectors
Design consultation
Mixing Systems
Our mixing system maximizes simplicity, ease-of-use, sterility, and affordability when storing, recirculating, and mixing biopharmaceuticals all in a single-use bag. A flexible, impeller-less mobile design allows easy integration into any process step. The mixing bag is fitted into a reusable conical drum and runs with a simple peristaltic pump, minimizing capital costs. This unique system rapidly recirculates to homogeneity in minutes.
Featured Video
Single-Use Mixing System
This animation shows how our single-use mixing system creates a completely sterile mixing and recirculation process, ensuring your buffer and media are mixed correctly and efficiently.
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Featured Technical Paper
Mixing Systems: How to Stay One Step Ahead of Biopharma Supply Chain Constraints
This paper examines single-use supply constraints that interfere with bioprocess operations and have been exacerbated by the COVID-19 pandemic and highlights Entegris solutions that can help minimize production delays.
Featured Data Sheet
Life SciencesOur bioprocess powderbags are an ergonomic, robust, closed solution for convenient filling, handling, storing, and transferring of powders used in media, buffer solutions, and active pharmaceutical ingredients (APIs).
Featured Content
Life Sciences
Microcarrier Separation Systems
This microcarrier separation bag can be integrated into your streamlined sterile process. The single-use separation system is comprised of a filter/mesh bag system using a simple peristaltic pump and does not require any other equipment. The bag size, mesh size, and pump settings (for trapping and breaking up cell clumps or capturing microcarriers) can be customized for your application. Our microcarrier separation system is sterilized using gamma irradiation and can be designed for hanging or tabletop configuration.
Featured Video
Featured Content
Life SciencesThis application note explains how, compared to conventional small-scale cell harvesting methods, Entegris' microcarrier and cell separation system can effectively separate cells from microcarriers and provide maximum cell recovery.
Motion Reactor Bags
Single-use bioreactors have become a flexible option in biopharmaceutical process designs. Select your preferred motion configuration and customize it by choosing the film, size, port number and geometry, tubing material, connector types, and more. We perform QC inspections from raw material to the final product, assuring performance safety, reliability, and regulatory compliance.
Featured Video
With the explosion of clinical trials expanding cells for new treatment modalities such as cell and gene therapies, motion bioreactors are in very high demand. Ross Acucena, applications director, and Donnie Beers, product manager, introduce our adaptable, motion bioreactor bags that can be configured for most rocking or motion platforms.
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Featured Content
Life SciencesFeatured Webinar
Addressing the Options and Challenges in Subvisible Particulate Contamination Monitoring in Single Use Systems
Key learning objectives:
- Contamination measurement for visible and subvisible ranges, evaluated using different techniques.
- Equipment and methods for testing for submicron particulates with sizes below the USP <788> limits of 10 and 25 µm.
- How ASTM E3230 provides a helpful framework for testing particulates below USP <788>
- Extraction method development and effects onresults
Tube Sets and Manifolds
Our tube sets and manifolds are custom manufactured using a quick-turn design-order-delivery process for single-use bioprocessing systems. We provide personalized support to ensure the solution meets your exact needs. Rapid production and consistent delivery minimize risk delays. Simple and complex designs offer nominal bag volumes, bag port options, diptubes, hanging rods, filter meshes, third party and customer-supplied components are all options. Standardization around materials of construction keep qualification simple.
Featured Video
Ross Acucena, applications director, and Donnie Beers, product manager, introduce our tube sets and manifolds that enable integrated single-use assemblies. We custom design solutions that fit the single-use system to your process and help reduce validation time.
Runtime: 02:50
Featured Content
Life Sciences
Barrier and Multilayer Bag Assemblies
2D Barrier Bag Systems – Triple barrier bag assemblies are ideal for medium to large, single-use applications. We custom design to your application, providing the flexibility needed to fit your application. Our quick-turn service is fast with a variety of sizes available from 50 L to 1000 L.
Featured Content
Life SciencesFeatured Content
Life SciencesDetailed listing of the various films our single-use assemblies are manufactured from. Ask our materials experts which film is best for your unique application.
Bioprocessing Containers
Chemical and Bioprocessing Containers – We have a variety of chemical packaging solutions to meet your compatibility, purity, and regulatory requirements. With and without liners, our rigid, bioprocessing support containers provide safe collection, transport, and storage of biopharmaceuticals. With volume sizes from 50 to 1000 liters, we have a solution for your most demanding shipping needs.
FluoroPure® HDPE Blowmolded Drums – Our blowmolded HDPE drums assure safe, high purity chemical transport around the world.
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Related Products
Combining product innovation with quick-turn customization to deliver a total solution for your upstream and downstream needs.
Quick-turn custom manufactured for single-use bioprocessing systems. We have solutions for secure fluid transfer, aseptic filling, sterile processing or storage, bioreactor filtration and support, and so much more.