Nanoparticles
Particle characterization is a critical tool for pharmaceutical companies. By carefully characterizing and monitoring particle size distribution during production, companies can ensure the quality, uniformity, performance, safety, and compliance of their products.
Benefits
Particle characterization tools can improve efficiency by providing data in real time, reducing costly lab experimentation, and enable process optimization.
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Ensure the quality and uniformity of pharmaceutical products.
The particle size of an active pharmaceutical ingredient (API) can have a significant impact on its bioavailability, stability, and safety. By carefully characterizing the particle size distribution of API, pharmaceutical companies can ensure that their products meet the required specifications.
Improve the performance of pharmaceutical products.
In some cases, the particle size of an API can be optimized to improve its performance. By understanding the relationship between particle size and product performance, pharmaceutical companies can develop more effective and efficient therapies.
Optimize the manufacturing process.
The particle size of the API can have a significant impact on the manufacturing process. Understanding the relationship between particle size and the manufacturing process using online measurement enables pharmaceutical companies to optimize their processes to improve efficiency and yield.
Featured White Paper
Nanoparticles Drive the Nanotechnology Revolution
Nanotechnology has been referred to as potentially being the next technical revolution that could change the modern world. This paper defines nanoparticles, their various uses, and the analytical techniques used for their physical characterization.
Animation
Nanoparticles
This animation explains how our Nicomp® DLS system provides more refined and accurate high-resolution size and zeta potential measurements to help enable successful nanoparticle formulation and manufacture.
On Demand Webinars
Particulate Contamination in Medical Devices and Single-use Systems
Subvisible particulate testing is critical to assess the safety of medical devices, and particulate contamination should be minimized to avoid possible negative health consequences to the patient.
A wide range of standards, USP tests, and FDA guidance documents provide test methods and acceptance criteria for particulate contamination in medical devices. In this webinar, Mark Bumiller discusses solutions to help meet these critical qualification requirements.
Nanoparticles for Drug Delivery
Join Mark Bumiller, technology manager, as he explores the analytical techniques used for nanoparticle characterization and its growing significance in novel drug delivery systems.
Featured Video
View the Nicomp DLS System
Video introduction of our Nicomp® DLS systems that use dynamic light scattering (DLS) technology to provide high sensitivity, high resolution size, and zeta potential of sub-micron particles.
Product Solutions
On-line particle size analyzer for nanoparticles and emulsions from 20 nm to 2 μm.
- Flexible protocols to optimize measurement to application based on dynamic light scattering (DLS)
- Automated sampling and measurement to eliminate operator and lab resources
- Continuous data to track changes in particle size distribution
- Easy data transfer to process monitoring control software
Measures the size and zeta potential of sub-micron particles.
- Uses dynamic light scattering (DLS) technology to provide high sensitivity, high resolution size, and Zeta potential results
- By selecting the optimum laser, detector, fluidics, and accessories, the Nicomp® DLS system is built to match your samples and application
- Nicomp Nano N3000 system is available for nanoparticle size analysis, and the Nicomp Nano Z3000 system is available for size and zeta potential analysis
A comprehensive portfolio of high accuracy and resolution liquid particle counters that determine particle size and concentration of your suspensions.
- Uses single particle optical sizing (SPOS) technology to provide extended dynamic size and concentration ranges
- Can be used as a liquid particle counter for contamination applications or as sophisticated particle size analyzer
- Highest sensitivity technology available to determine tails of distribution such as large particle counts (LPC) in CMP slurries, protein aggregates, or tails of emulsions (PFAT5)
- Fast, multi-channel pulse height analyzers that can report results in up to 1024 size bins
- Several fluidics configurations are available to deliver the sample to the sensor directly or with auto dilution to avoid coincidence errors
Data Sheet
Life SciencesApplication Note
Life SciencesThis application note explores the growing purity needs in single-use systems used in pharmaceutical and biopharmaceutical industries, and analyzes particulate contamination levels in Aramus™ bag assemblies using the AccuSizer® SPOS system.
Application Note
Life SciencesApplication Note
Life SciencesApplication Note
Life SciencesLearn more about our nanoparticle measurement solutions
Our particle sizing technologies can accurately and rapidly measure both quantity and size to meet these urgent needs.
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