Cell Expansion and Cryogenic Banking
Each phase of a bioprocess demands consistent product quality and supply to meet regulatory, safety, and production scale requirements. Single-use technologies enable completely closed systems. These reduce the risk of contamination and improve process efficiency during seeding, expansion, harvest, and cryopreservation. Manufacturing and preservation improvements are driven by product viability, recovery, safety, and process efficiency. Cryopreservation and cell banking play a significant role in the efficiency of bioprocesses. They provide larger volumes of highly concentrated cells to start production runs, shortening seed train by several weeks and reducing the risk of contamination.
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Featured Video
Cell Expansion
Entegris offers a wide variety of customizable solutions such as single-use bags, tube sets, and manifolds for your high density cell banking and cell and gene therapy processes. Shorten your seed trains with our high quality, freezable, transportable bags. Runtime: 00:30
Featured Webinar
Creating a Closed-Process, Semi-Automated Workflow for Human MSC Expansion, Harvest, and Final Fill
Join Donnie Beers (Entegris) and Kyle Harvey (MED Institute, Inc.) as they discuss workflow challenges when scaling up cell and gene therapy production. Learn about creation and use of semi-automated modular workflows and when to deploy off-the-shelf consumables.
Technical Notes
In this technical note, we’ll explore the chemical compatibility of Aramus assemblies with DMSO, which is commonly used as a cryopreservant in cell and gene therapy.
The objective of this technical note is to determine the cryogenic temperature compatibility of the Aramus bag assembly material through freezing and drop testing after 24-hour minimum immersion in the liquid nitrogen vapor phase.
Product Solutions
Our single-use solutions support both fed batch and continuous bioprocessing for mAbs, vaccines, bioconjugates, cell therapies, and gene therapies.
We offer a variety of single-use products including bag assemblies, custom tube sets and manifolds, and filters for use in many different cell separation processes.
We offer a variety of single-use products for use in many media preparation processes. Solutions include bag assemblies, custom tube sets and manifolds, mixing systems, tubing and pipe, and liquid filters.
Aramus single-use bag assemblies are a flexible and dependable choice for cold bioprocessing applications. We also offer a range of accessory products such as storage cassettes and shells, and tube sets and manifolds to make your freeze/thaw process more flexible, secure, and efficient.