Reference Materials ( 309 )

Delivers superior airflow at low pressure drop with lower blockage risk in moist air sterile filtration

Delivers superior airflow at low pressure drop with lower blockage risk in moist air sterile filtration

The Entegris Flex Mixing System is a single-use system for the mixing of powders and liquids or liquids and liquids in a sterile, closed system. The mixing utilizes a large peristaltic pump and is effective for mixing solutions up to 200 L.

A comprehensive guide for ordering NOWPak® liner based bottle systems. Includes detailed information on the system components and how they work together to deliver your materials with purity, safety, and process efficiency.

Comprehensive manual provides detailed instructions for proper storage, use, pressurization, installation, and change out of NOWPak® and PDMPak® liner-based bottle systems.

Learn how testing alternate materials and methods can lead to reduced costs and improved outcomes in freeze/thaw processes. Runtime: 58:29

Pre-cleaned, one-ply, heat-sealed PTFE T650 liner in 20-liter and 200-liter sizes for use with NOWPak bottle systems and canister systems used in high-purity solvent and solvent mixes for laboratory and life sciences markets.

Liner-based bottle system with a pre-cleaned, two-ply, heat-sealed PTFE T420 liner.

Replacement PTFE T420 liner designed for use with our NOWPak® liner-based canister and bottle systems. Available in 1-, 4-, 10-, and 19/20-liter sizes.

ErgoNOW ™ connectors support pressure, pressure assist, or pump dispense of chemicals with misconnect prevention and an ergonomic design for ease of use

NOWPak® liner-based canister system closures with their two-piece aluminum design and PTFE seals protect critical materials within filled canister systems.

NOWPak® liner-based canister system closures are available with 63 mm buttress thread and fit 4- to 40-liter canister sizes.

FluoroLine® ultrapure tubing is made from 100% virgin high purity PFA. It is ideal when the utmost purity and chemical resistance is required.

FluoroLine® ultrapure tubing is made from 100% virgin high purity PFA. It is ideal when the utmost purity and chemical resistance is required.

Explains how our AccuSizer® Syringe Injection System (SIS) is designed to meet and exceed all requirements in USP <788> Particulate Matter in Injections test, which is used to quantify the count and size of subvisible particles in parenteral drugs.

A part number guide for selecting the right 55 gallon (200 liter) trilayer HDPE drum.

By creating a completely sterile process from start to finish, our mixing system maximizes simplicity, ease-of-use, and affordability when storing, recirculating, and mixing biopharmaceuticals within a single-use bag.

IsoSciences continues to produce the highest quality isotopically labeled products and to expand its isotopically labeled product offering.

In this short animation, learn how sterile filtration is used in sensitive biotech applications to help deliver pure products with reliable yield. Runtime: 01:26

A part number guide for selecting the right chemical dispense system

This guide delves into the intricacies of filtration within single-use systems.

Pharmsteri™ II PES 液体囊式滤器旨在为终端用户 在关键的液体处理工序中提供高流量和高载量性 能。

Mixers play an essential role during both upstream and downstream processing, specifically in the formulation of media and buffers.

Comprehensive user guide for properly installing the Pharmsteri™ II PES 0.22 buffer capsule filters. Includes product acceptance, installation, wetting, integrity testing, sterilization, troubleshooting, storage and disposal instructions.

IntelliCap™ closures are used together with the NOWPak® liner-based bottle system to seal the bottles after they are filled with chemical.

Entegris Pharmsteri™ II GSV UPE 0.22 µm vent capsule filters are designed to provide end-users with high flow, sterile barrier, and enhance hydrophobicity properties for use in critical gas and vent applications.

应特格Pharmsteri™ II GSV UPE 0.22µm嚢式滤器旨在为终端用户在关键气体过滤和通风口应用点提供高通量，强疏水性，且能作为无菌屏障的滤芯。

Learn how Entegris Blast Freezing Shells add strength, ergonomics, and reliability to Aramus™ 2D Bag Assemblies — even at cryogenic extremes. Runtime: 0:38

When paired with Entegris Plate Freezing Shells, Aramus™ 2D Bag Assemblies become even more robust and reliable, able to withstand falls and impacts even after exposure to cryogenic temperatures. Runtime: 0:37

The MCPA counter connects to your computer via USB cable. On initial connection, your computer will provide 5 V through the USB cable to initiate a connection to the MCPA. However, the MCPA is sensitive to instability on the USB connection (VBUS) that can cause the connection to fail.

ALLpaQ containers are rigid plastic units specifically engineered for the storage and transportation of large-volume liquids.

In this work, we performed series of tests on phosphoramidites with various protecting groups to identify chemically unstable and high energy reactions. These tests identify sufficient safety margin about undesired and potential thermal decomposition.

Single-use systems are gaining traction in life sciences research and manufacturing, but there’s potential for them to adsorb contaminants. In our on-demand webinar “Addressing the Options and Challenges in Subvisible Particulate Contamination Monitoring in Single-Use Systems” presented by Entegris Technology Manager Mark Bumiller and hosted by BioProcess Online, you’ll learn how to use Entegris equipment to monitor and extract particulates from single-use bags and tubing. Register to view now! Runtime: 01:00:02

For over 50 years, we have been committed to solving our customers' most demanding process challenges through a broad solutions portfolio, collaborative and innovative product development, and a focus on science and applications knowledge. Read the facts here.

For over 50 years, we have been committed to solving our customers' most demanding process challenges through a broad solutions portfolio, collaborative and innovative product development, and a focus on science and applications knowledge. Read the facts here.

In this guide, users will learn how to operate the Aramus Aseptic Sampling Bag. This equipment allows users to easily withdraw a 1-3 ml sample from a single-use bag without contamination, while pushing excess sample material back into the original container. Use of the sampling bag helps users preserve sample quality while saving on costs in the most sensitive life sciences applications. Our integrity tested, gamma stable Aramus Aseptic Sampling Bag is always 100% integrity tested to ensure great performance even at extreme temperature -196°C to 121°C (-321°F to 250°F). Runtime: 01:48

Conserve every drop of your high-value samples with the Entegris in-line aseptic sampling system. Runtime: 00:29

Entegris offers a wide variety of customizable solutions single-use bags, tube sets, and manifolds for your high density cell banking and cell and gene therapy processes. Shorten your seed trains with our high quality, freezable, transportable bags. Runtime: 00:30

The Microcarrier Cell Separation system facilitates separation processes via a streamlined, single-use filter/mesh bag system and peristaltic pump. Customize the bag size, mesh size, and pump settings and use our bag for a wide array of applications such as retaining aggregate cells or microcarrier beads, cell washing, and harvest, all while achieving the same or better performance as alternative separation methods. Runtime: 00:30

Entegris' motion bioreactor bags are designed for mammalian and plant culture cell lines with extended mixing times, as well as growing NSO and other cholesterol sensitive clones. Customize the dimensions and ports and be confident that your bag is manufactured to the highest quality specifications. Runtime: 00:30

Aramus™ single-use 2D bags, combined with the Entegris plate freezing shells, provide an easy-to-use, ergonomic, and reusable secondary container for high throughput plate freezer systems to enable rapid freeze-thaw workflows.

Aramus™ single-use 2D bags, combined with the Entegris blast freezing shells, provide an easy-to-use, lightweight, and reusable secondary container solution for use with controlled rate convection or standard lab cold-wall freezers.

Entegris offers cleanable, metal freezing shells for use with any commercial, controlled rate plate freezer for bulk drug freezing applications.

Entegris offers lightweight, plastic freezing shells for use with static, blast, ULT freezers, and controlled rate freezing chambers for bulk drug freezing applications.

From bioreactor harvest to cryopreservation, Aramus completely closed banking manifolds provide convenient fill and storage in liquid nitrogen vapor.

Amanda Olson, technical writer for AMH instrumentation at Entegris, talks about our Mini DLS online particle sizing system. Watch the video to learn what makes the Mini DLS a vital and interesting technology both for its designers and our valued customers. Runtime:03:14

Entegris cassette and overwrap solutions allow you to protect and store your high value product in liquid nitrogen applications.

Our bioprocess powderbags are an ergonomic, robust, closed solution for convenient filling, handling, storing, and transferring of powders used in media, buffer solutions, and active pharmaceutical ingredients (APIs).

Pre-cleaned, polyethylene diptube assembly for NOWPak® liner-based canister systems

Novel therapeutics often rely on advanced blast freezing technologies, but it can be difficult to develop processes around complex freeze/thaw operations. As experts in cold-chain and blast freezing research, Entegris and FARRAR™ offer this on-demand webinar as an opportunity for users to improve their understanding of emerging technologies and techniques. Runtime: 01:09:41

The “tail” of a particle size distribution refers to particles several standard deviations removed from the mean of the standard Gaussian distribution. It can have a significant effect on product quality and performance.

Learn how to select sterile filtration solutions for single or multi-use life sciences applications with Cris Rios, Senior Field Applications Engineer. Entegris’ science-driven data helps implement optimized filter selection without the risk of compromising sterility in your products. Runtime: 02:07

It’s difficult to scale cell and gene therapy production using all-in-one processing systems. That’s because the budget level and personnel required may make it cost-prohibitive to increase capacity. In this webinar, we’ll discuss the benefits of a decentralized manufacturing strategy. Using a real-life case study, we’ll demonstrate how this approach can help users scale from lab to commercial levels. Runtime: 31:25

See how to select the best filters for your life sciences application with Chris Rios, Entegris Senior Field Applications Engineer. Understanding the choices between membrane properties will help optimize compatibility and performance in your process. Runtime: 01:30

Find out how to select a prefilter for sterile filtration applications and recognize the advantages between various membrane morphologies with Chris Rios, Entegris Senior Field Applications Engineer. Runtime: 01:17

Discover how to minimize product loss from hold-up-volume in scale-up activities with Cris Rios, Senior Field Applications Engineer. Entegris’ sterile filter designs minimize product loss in life sciences applications at each each stage of development and production. Runtime: 00:56

Tubing material reference document for use in Life Sciences upstream and downstream applications.

This validation guide addresses key requirements needed to validate Aramus™ bag assemblies for use in regulated applications. It contains sourcing, testing, and regulatory compliance summaries that validate Aramus bag assemblies meet those requirements.

Entegris provides a wide range of particle size and count solutions to any business manufacturing or using silica suspensions.

Made from a high-grade, gamma-stable fluoropolymer that maintains mechanical integrity in frozen applications to -85°C, our Aramus™ single-use 2D bag assemblies provide higher purity, greater compatibility, and increased safety for critical process fluids and final products.

Discover how Entegris can help achieve end to end process excellence with our single-use solutions.

Keep product control in your hands with our quick-turn custom manufactured solutions for specific bioprocessing applications. We have solutions for secure fluid transfer, aseptic filling, sterile processing or storage, bioreactor filtration and support, and much more.

This video introduces the Mini DLS system, an online particle measurement solution that sits diverts samples from your process stream to provide data in near real-time.. Runtime: 01:50

Detailed overview of our AccuSizer® A7000 SPOS systems designed as liquid particle counters for contamination applications or as sophisticated particle size analyzers of suspensions.

Entegris Double Chime Low Residual Drums are designed for sensitive materials critical to the semiconductor, storage, flat panel display, and life sciences industries. They provide the highest standard of purity and reliability while minimizing wasted chemistry..

ND-CD series pressure dispense connectors provide a clean, convenient, and completely sealed method for dispensing chemicals from NOWPak® canisters.

As shown by the global rollout of the COVID-19 vaccine, the cold chain is a critical part of the pharmaceutical supply chain. How can we make it work better? In this webinar, presented by BioProcess Online and sponsored by Entegris, we’ll demonstrate how emerging technologies can make the cold chain safer and more reliable while improving patient outcomes. Using our quantitative analyses, you’ll understand how controlled-rate shelf freezers, single-use bags, reusable protective shells, and ergonomic workflow solutions can help meet critical end-user objectives. Runtime: 33:49

Getting real-time data from an online source is vastly more efficient than sampling the process stream and using an offline laboratory. With precise online measurement, process changes can be made in minutes rather than hours or days.

Entegris introduces the Mini DLS system. This technology, powered by dynamic light scattering, lets users eliminate hours of work in offline labs. Use real-time results to improve quality and performance. Runtime: 01:00

In August of 2023 Entegris released AccuSizer® software version 3.1.4.0 that includes several new features.

The Entegris AccuSizer is the most accurate and high-resolution particle sizing technique used to characterize powders for AM.

Pharmsteri™ polypropylene cartridge filters provide economical filtration for removing particulate and colloidal contaminants in various pharmaceutical as well as food and beverage applications.

Additive manufacturing (AM), or three-dimensional (3D) printing can be performed using various materials including liquid resins, polymers, and powder metals. When using polymers and metal powders, the particle size distribution is important for processability and final part quality. The powder particles act as building blocks, and their size affects the packing density, surface area, and flowability of the powder bed. A variety of particle size analysis techniques can be used to determine the powder size distribution, including laser diffraction and single particle optical sizing (SPOS). This webinar will explain the advantages and disadvantages of both techniques and provide examples of results and data interpretation. Runtime: 58:42

This quick start guide provides a procedure for cell banking.

This application note examines the benefit of using fluoropolymer film for the handling and storage of high value oligonucleotides-based payloads such as ssDNA aptamer and its applications in precision biological engineering/synthetic biology, in vitro diagnostic and medical space industries.

Constructed of PTFE pleated membranes with polypropylene (PP) supports, these filters provide unmatched durability and cleanliness in point-of-tool and dispense applications involving solvents, DI water, and dilute acids and bases.

This video will show you how utilizing high-density cell banking workflows in combination with your already intensified upstream process can further enhance your process productivity while reducing contamination risks. Runtime: 11:31.

High-density cell banking (HDCB) involves freezing high concentrations of cells in large single-use bags. It increases productivity and reduces manufacturing costs by eliminating intermediate steps. HDCB also reduces the risk of contamination and the number of consumables needed, while enabling rapid cell recovery and high viability.

Learn more about how Entegris supports each stage of life sciences manufacturing.

This webinar will examine the advantages of fluoropolymer film as material of choice for the storage and development of high value oligonucleotide-based payloads such as an ssDNA aptamer. Nucleic-acid-based therapies, such as DNA, antisense oligonucleotides, small interfering RNAs (siRNA), aptamer probes, and messenger RNA (mRNA), have been widely used in diverse biomedical applications. Runtime: 54:28

Our robust 3D multilayer bioprocess assemblies are sterilized using gamma irradiation and can be integrated into a variety of large volume single-use biopharmaceutical applications. Customization is available.

The preparation of new biologically active entities has generated immense study in the field of phosphorylation. Here is a mini review.

Savana® 334 PTFE cartridge filters are constructed of PTFE pleated membranes with polypropylene supports to provide durability and high flow performance for filtration of process fluids in electronic industry.

NOWPak® Liner-based Canister Systems provide safe and efficient delivery of critical process materials. 4 to 200 liter sizes.

Bioprocessing for monoclonal antibodies (mAbs) and other life sciences modalities relies on effective and efficient sterile filtration processes to remove contaminants that compromise product purity and yield in both small-batch systems and rapid large-scale manufacturing.

In this webinar, Chris Rios, Entegris senior field applications engineer, discusses how filtration manufacturers optimize materials for performance and integration within single-use systems, where product performance and quality are vital.

This guide walks you through the steps for making zeta potential measurements using our Nicomp® DLS system. Guide includes software setup, sample measurement, sample preparation, and system verification.

The NS60 liner conforms to the interior of the canister minimizing stress improving liner strength and durability and maximizing chemical fill volume.

NOWPak® Liner-based Canister Systems provide safe and efficient delivery of critical process materials. 4 to 200 liter sizes.

This Pharma IQ report looks at the ways pharmaceutical companies can improve their manufacturing processes and make efficiencies, from the concept stage through to market.

This validation guide addresses key requirements needed to validate Pharmsteri™ II PES 0.22 buffer capsule filters for use in regulated applications. It contains sourcing, testing, and regulatory compliance summaries that validate Pharmsteri II PES buffer capsule filters meet those requirements.

This material is a high-purity precursor for surgical wound closure products in medical and veterinary applications.

Detailed listing of the various films our single-use assemblies are manufactured from. Ask our materials experts which film is best for your unique application.

This comprehensive user manual instructs users on properly unpacking, filling, freezing, storing, handling, and shipping Aramus™ standard bag subassemblies and full assemblies. Includes safety, warranty, and terms and conditions of sale.

Entegris is your partner in delivering innovative specialty chemicals to develop and provide advanced optical materials for enhancing vision.

Comprehensive user guide for properly installing the Pharmsteri™ PES disposable filters. Includes product storage, installation, flushing and wetting, integrity testing, sterilization, replacement, and disposal instructions.

This Cold Chain Guidance Tool is an interactive learning experience that identifies areas of interest based on the users specific operations. Entegris guides the process of configuring freeze/thaw (F/T) solutions for biologic treatments and therapies based on your specific scenario and needs. Our Life Sciences Technology Center provides everything needed to make educated decisions about what freezing process and products best fit your needs.

Entegris provides useful solutions in every step of oligonucleotide manufacturing. We enable ultra-high purity, high-yield processing that allows cost-effective commercialization of RNA therapeutics.

Mark Bumiller, technology manager, and Joy Xiaohui Chen, senior application engineer, discuss particulate contamination as an important consideration in pharmaceutical production, and even more so in bioprocess production and delivery as well as in ophthalmic applications.

This application note explains how, compared to conventional small-scale cell harvesting methods, Entegris' microcarrier and cell separation system can effectively separate cells from microcarriers and provide maximum cell recovery.